An analysis of treating anaphylaxix
The pharmacological treatment administered was assessed in relation to EAACI guidelines recommendations [ 12 ]. The mortality rate during our study period was 0.
An analysis of treating anaphylaxix
In this scoring system is possible to graduate the reaction also if only single symptoms, such as hypotension, are registered, and it refers to key symptoms that are absolute indications for adrenaline administration. Since the patient died before arriving to the ED we chose to describe the findings independently and therefore this case is not included in further analysis. To our knowledge, only few studies have assessed anaphylaxis prospectively [ 5 , 13 , 15 ]. Adrenaline levels showed a double peak, with parallel changes in the heart rate. Furthermore, all medical doctors in the ED and APW were informed to refer all patients with suspicion of anaphylaxis. Furthermore, patients may have attended other hospitals during the study period. However, it has been questioned whether the needle length of the autoinjectors is sufficient to achieve genuine intramuscular delivery and optimal bioavailability.
If a patient had multiple contacts with anaphylaxis at the ED or the APW over the study period, data from the first contact was used.
To identify anaphylaxis cases, records from all patients with clinical suspicion on anaphylaxis or a related diagnosis according to the International Classification of Diseases 10 and from patients treated at the emergency care setting or at prehospital level with adrenaline, antihistamines or glucocorticoids were reviewed daily.
Statistical analysis Statistical analysis was performed with Stata IC Furthermore, patients may have attended other hospitals during the study period.
J Allergy Clin Immunol Pract. To our knowledge, only few studies have assessed anaphylaxis prospectively [ 51315 ]. Inhaled adrenaline was also assessed. Overall, the case fatality is reported below 0.
Anaphylactic shock treatment protocol
Food has been reported as the most common elicitor in children, while drugs and venom are more frequent in adults [ 2 , 3 , 9 ]. The aim of this prospective study was to evaluate patients with symptoms, diagnosis and treatment suggestive of anaphylaxis at admission to the emergency care setting. Epub Nov 3. Therefore, the estimates are minimum figures. Overall, the case fatality is reported below 0. METHODS: This randomized, open-label, crossover study compared the impact of adrenaline administration at 2 sites in the thigh of 18 normal weight male volunteers, using either Anapen or the prefilled syringe; in addition, we studied the treatment of 12 overweight women with Anapen. Even a head-to-head comparison would be very interesting! To identify anaphylaxis cases, records from all patients with clinical suspicion on anaphylaxis or a related diagnosis according to the International Classification of Diseases 10 and from patients treated at the emergency care setting or at prehospital level with adrenaline, antihistamines or glucocorticoids were reviewed daily. The proportion of individual patients with anaphylaxis in the APW was calculated to 0. In the prehospital setting, the response to an acute request of prehospital assistance is a two-tiered system, in which an ordinary ambulance manned with two emergency medical technicians EMTs is supplied by the Mobile Emergency Care Unit MECU. Our primary objective was to estimate the period prevalence and the Incidence Rate IR of anaphylaxis during — in children and adults admitted to the emergency care setting of Odense University Hospital. Anaphylaxis represented 0. Adrenaline was administered in a low proportion of the patients with moderate to severe anaphylaxis.
The lifetime prevalence of anaphylaxis in the general population is estimated to be about 0. Anaphylaxis represented 0. All the matched records were reviewed to recognize the possible anaphylaxis cases.
Results Numbers of individuals at each stage of the study and reasons for exclusion are presented in Fig. Nevertheless, the diagnosis of anaphylaxis may be difficult in patients with many symptoms, without a certain history of allergy and in the absence of symptoms from the skin and mucosal tissue [ 11011 ].
based on 44 review